Research Article | DOI: https://doi.org/-

Pediatric Brain Tumours: Biological Mechanisms, Diagnostic Innovations, and Evolving Treatment Paradigms

  • Ananya Deshmukh *

1.Department of Pediatrics, Sunrise Institute of Medical Sciences, Pune, Maharashtra, India.

2.Division of Pediatric Neuro-Oncology, Children’s Advanced Care Hospital, Bengaluru, Karnataka, India 

*Corresponding Author: Ananya Deshmukh

Citation: A Deshmukh, Pediatric Brain Tumours: Biological Mechanisms, Diagnostic Innovations, and Evolving Treatment Paradigms, International Journal of Medical Sciences and Research, ACP Publishers, 1(1).

Copyright : © 2026 Ananya Deshmukh, this is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Received: 15 May 2026 | Accepted: 23 May 2026 | Published: 27 May 2026

Keywords: paediatric brain tumours, medulloblastoma, diffuse intrinsic pontine glioma, neuro-oncology, molecular diagnostics, targeted therapy

Dr. Pediatric Brain Tumours: Biological Mechanisms, Diagnostic Innovations, and Evolving Treatment Paradigms

Paediatric brain tumours represent the most common solid malignancies in children and remain a leading cause of cancer-related mortality in this population. Unlike adult brain tumours, paediatric neoplasms exhibit distinct molecular profiles, developmental origins, and therapeutic responses. This review provides a comprehensive overview of paediatric brain tumours, including epidemiology, molecular pathogenesis, clinical features, diagnostic approaches, and current treatment strategies. Emphasis is placed on recent advancements such as molecular classification, minimally invasive diagnostics, targeted therapies, and immunotherapeutic approaches. The article also highlights ongoing challenges, including treatment-related neurotoxicity and the need for precision-based pediatric oncology.

Keywords:
paediatric brain tumours, medulloblastoma, diffuse intrinsic pontine glioma, neuro-oncology, molecular diagnostics, targeted therapy

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